Q42 - Carrier Probability in an Autosomal Recessive Pedigree
This pedigree shows the occurrence of a rare disease phenotype (shown in black) with full penetrance. The genetic disorder is caused by a recessive autosomal allele d. Pedigree of family with an autosomal recessive disease.
Figure 1.
Using the information and data, determine which of the statements are true or which are false.
A. The probability that II-4 carries the disease allele is 0.50
B. II-2 and II-4 have the same probability of carrying the disease allele
C. If assume that II-5 does not carry allele d, the probability that III-3 carries this allele is 0.30 or higher
D. If we assume, that II-5 is heterozygous and III-3 has the disease, then the probability that II-4 is a carrier is 0.5
Question reproduced from IBO 2015, Theoretical Exam A, licensed under CC BY-NC-SA 4.0 - attributed to the International Biology Olympiad. Open the full exam PDF · Community solutions (unofficial)