Q15 - Enzyme Rate, Inhibition, and Allosteric Kinetics
The figure below depicts the relation between substrate concentration and enzyme reaction rate.
Figure 1.
Using the information and data, determine which of the statements are true or which are false.
A. At saturating levels of substrate, the rate of an enzyme catalysed reaction is proportional to the enzyme concentration.
B. If enough substrate is added, the Vmax of an enzyme catalysed reaction in the presence of a non-competitive inhibitor can be the same as Vmax of the reaction in absence of the inhibitor.
C. The rate of an enzyme catalysed reaction in the presence of a rate-limiting concentration of substrate decreases with time.
D. The sigmoidal shape of the V versus [S] curve obtained with allosteric enzymes indicates that the affinity of the enzyme for substrate decreases as the substrate concentration is increased.
E. The affinity of an allosteric enzyme for substrate varies with enzyme concentration.
Question reproduced from IBO 2018, Theoretical Paper 2, licensed under CC BY-NC-SA 4.0 - attributed to the International Biology Olympiad. Open the full exam PDF · Community solutions (unofficial)