Q2 - Classifying Endo-type and Exo-type Hydrolases by Biological Role
Hydrolases that degrade biopolymers can be categorized into two types: (1) endo-type that hydrolyzes the interior bonds of the polymer, and (2) exo-type that releases the end unit from the polymer. These exo-type and endo-type hydrolases are often linked to their biological roles. Choose (1), if the enzyme mentioned below (A-D) is endo-type, and choose (2) if it is an exo-type.
Using the information and data, determine which of the statements are true or which are false.
A. Digestive proteases in stomach such as pepsin
B. Proteases that cleave off the translocation signal peptide
C. Proofreading nuclease in the DNA polymerase that removes misincorporated nucleotides during DNA replication
D. Cas9 nuclease of the CRISPR-Cas9 system for genome editing
Question reproduced from IBO 2020, Theoretical Exam 2, licensed under CC BY-NC-SA 4.0 - attributed to the International Biology Olympiad. Open the full exam PDF · Community solutions (unofficial)